Combined Measurement of Serum Sialyl Lewis X with Serum CA15-3 in Breast Cancer Patients
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چکیده
منابع مشابه
Clinical Value of Serum S100A8/A9 and CA15-3 in the Diagnosis of Breast Cancer
Background and Objective: S100A8/A9 is a heterodimer calcium-binding protein which is involved in tumor cell proliferation, adhesion and invasion, and is proposed as a biomarker for better diagnosis and prognosis in many cancers. The aim of this study was to evaluate the simultaneous serum-based level of S100A8/A9 and CA15-3 as well-illustrated cancer biomarkers, as well as the...
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CA15-3 is a high-molecular-mass mucin-like glycoprotein expres¬sed at the luminal surface of most secretary epithelia and associated with mammary tumors (Taylor et al., 2002). Increased levels were observed in patients with breast cancer (Kobayashi et al., 1989). Clinical uses of this marker include monitoring of patients with breast cancer (Duffy, 1999; Duffy et al., 2006), prognosis (McLaughl...
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Sialyl 6-sulfo Lewis X determinant has been described recently as a major ligand for L-selectin on high endothelial venules of human peripheral lymph nodes. From our investigation of its distribution in human colorectal cancer tissues and cultured colon cancer cells, the sialyl 6-sulfo Lewis X determinant was preferentially expressed in the nonmalignant colonic epithelia rather than cancer cell...
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Breast cancer (BC) is the second leading cancer causing death in women (Siegel et al., 2012). Despite the widespread use of the screening methods, 5% of the cases were diagnosed at the advanced stage. Spread of the BC cells native of the primary location through circulation is one cause leading to metastasis (Jacob et al., 2007; Fehm et al., 2008). Presence of the circulating tumor cells (CTC) ...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Oncology
سال: 2006
ISSN: 1465-3621,0368-2811
DOI: 10.1093/jjco/hyi235